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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
15.76
Human Site:
S206
Identified Species:
24.76
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
S206
N
V
V
K
L
L
S
S
R
R
T
Q
D
R
K
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
S206
N
V
V
K
L
L
S
S
R
R
T
Q
D
R
K
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S319
N
V
V
K
L
L
S
S
R
R
T
Q
D
R
K
Dog
Lupus familis
XP_548434
951
104664
G268
N
V
V
K
L
L
G
G
Q
R
T
Q
D
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
G199
N
V
V
K
L
L
G
G
Q
R
M
Q
D
R
K
Rat
Rattus norvegicus
O08874
985
112050
S247
N
V
M
K
L
L
G
S
G
K
V
T
D
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G306
N
V
V
K
L
L
G
G
R
R
L
Q
D
R
K
Chicken
Gallus gallus
XP_422357
1013
114806
S272
N
V
M
K
L
L
G
S
G
K
V
T
D
R
K
Frog
Xenopus laevis
Q7ZX15
486
56292
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
V234
N
V
V
K
Q
L
G
V
R
K
V
Q
D
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
K73
V
H
Q
V
N
G
H
K
F
M
A
T
F
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
G130
H
V
V
V
E
M
H
G
T
N
V
E
D
V
H
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
P125
K
R
I
Q
E
L
P
P
D
Q
T
R
F
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
Q198
P
N
D
I
M
D
N
Q
Q
P
K
F
R
R
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
L186
G
I
E
K
M
V
Q
L
Y
Q
M
E
G
D
K
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
100
80
N.A.
73.3
60
N.A.
80
60
0
60
N.A.
0
N.A.
20
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
80
73.3
N.A.
80
73.3
0
73.3
N.A.
6.6
N.A.
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
7
0
0
7
0
0
0
67
7
0
% D
% Glu:
0
0
7
0
14
0
0
0
0
0
0
14
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
14
0
0
% F
% Gly:
7
0
0
0
0
7
40
27
14
0
0
0
7
0
0
% G
% His:
7
7
0
0
0
0
14
0
0
0
0
0
0
0
7
% H
% Ile:
0
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
67
0
0
0
7
0
20
7
0
0
0
67
% K
% Leu:
0
0
0
0
54
67
0
7
0
0
7
0
0
7
0
% L
% Met:
0
0
14
0
14
7
0
0
0
7
14
0
0
0
0
% M
% Asn:
60
7
0
0
7
0
7
0
0
7
0
0
0
7
0
% N
% Pro:
7
0
0
0
0
0
7
7
0
7
0
0
0
0
0
% P
% Gln:
0
0
7
7
7
0
7
7
20
14
0
47
0
0
7
% Q
% Arg:
0
7
0
0
0
0
0
0
34
40
0
7
7
67
14
% R
% Ser:
0
0
0
0
0
0
20
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
34
20
0
0
0
% T
% Val:
7
67
54
14
0
7
0
7
0
0
27
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _